Human chorionic gonadotropin (hCG) concentrations during the late first trimester are associated with fetal growth in a fetal sex-specific manner.

The association of maternal hCG with crown rump length In the subset of women with regular cycles and known last menstrual period, in which CRL measurement was available, hCG concentrations during early pregnancy were negatively associated with CRL, but this analysis did not reach statistical significance (Supplemental Fig. 4; N = 1526; P for interaction fetal sex = 0.10).

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