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Systemic autoimmunity induced by the TLR7/8 agonist Resiquimod causes myocarditis and dilated cardiomyopathy in a new mouse model of autoimmune heart disease.

Dis Model Mech · 2017 · PMC5374321 · PMID 28250051

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Mild morphological changes indicative of the onset of LV dilation were observed in individual mice, particularly of the NOD/ShiLtJ background, but these did not reach statistical significance ( Fig. 6 E).

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