Although ipragliflozin and alogliptin monotherapies tended to reduce atheromatous plaque volume in the aortic root, these changes did not reach statistical significance ( p = 0.1–0.2).
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Combination Therapy with a Sodium-Glucose Cotransporter 2 Inhibitor and a Dipeptidyl Peptidase-4 Inhibitor Additively Suppresses Macrophage Foam Cell Formation and Atherosclerosis in Diabetic Mice.
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