Reduced blood pressure-lowering effect of catheter-based renal denervation in patients with isolated systolic hypertension: data from SYMPLICITY HTN-3 and the Global SYMPLICITY Registry.

In the subgroup of patient with ABPM measurements ( n = 305), the change in 24-h ambulatory SBP in ISH patients is numerically lower than that in CH patients, but the difference did not reach statistical significance (−1.9 mmHg, 95% CI −5.8, 2.0, P = 0.337) ( Figure 2 ).

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