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Tenofovir has inferior efficacy in adefovir-experienced chronic hepatitis B patients compared to nucleos(t)ide-naïve patients.

Clin Mol Hepatol · 2017 · PMC5381841 · PMID 28190329

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In the HBeAg-negative group, the CVS was lower in the adefovir-experience group, although it failed to reach statistical significance ( Table 5 ).

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