Mouse fitness measures reveal incomplete functional redundancy of Hox paralogous group 1 proteins.

Initially, Hoxa1 B1 founders obtained fewer territories than controls leading to a marginally significant difference at the model intercept (GLMM; Z = 1.96, p = 0.050; S3 Table ).

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The distortion of Hoxa1 B1(g)/B1(g) segregation was noticeable, although it did not reach statistical significance.

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Though an overall trend emerged that male control mice were more likely to dominate a territory than Hoxa1 B1 males, the instability of the pattern over time makes it difficult to link competitive ability to the observed reproductive deficiency.

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