Control of Food Intake by Gastrointestinal Peptides: Mechanisms of Action and Possible Modulation in the Treatment of Obesity.

J Neurogastroenterol Motil · 2017 · PMC5383113 · PMID 28096522

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did not reach statistical significanceno p-value reported

These results on food intake and body weight are extended by animal studies investigating the effects of bilateral DBS of the LHA in obese Zucker rats, which decreased food intake after 15 days of stimulation associated with a slight reduction of body weight that did not reach statistical significance. 198 Taken together, monopolar stimulation seems to be necessary in order to induce weight loss.

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