Barely Significant
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Environmental pollutants, a possible etiology for premature ovarian insufficiency: a narrative review of animal and human data.

Environ Health · 2017 · PMC5384040 · PMID 28388912

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a significant trendno p-value reported
An epidemiological study from 616 Italian non menopausal women exposed to the Seveso explosion found a significant trend for an earlier age at menopause in the four first quintiles of level of exposure to TCDD at the time of explosion but not for the 5 quintiles, suggesting a nonmonotonous dose-related effect [ 101 ].

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