Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy.

PLoS Genet · 2017 · PMC5386306 · PMID 28346493

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp<10 −6actually significant

B) led to a robust and highly significant (p<10 −6 ) expressional reprogramming of the genes functionally linked to olfaction (36 DEGs), olfactory response (35 DEGs), signal transduction (51 DEGs) and cell-cell communication (52 DEGs).

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did not reach statistical significanceno p-value reported

As a consequence, the average ratio of the basal pERK/ERK was slightly increased in mutant slices ( Fig 5C ; 120±7% of control), but this difference did not reach statistical significance.

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