Mitotic control of human papillomavirus genome-containing cells is regulated by the function of the PDZ-binding motif of the E6 oncoprotein.

Indeed, the combined frequency of these abnormalities was statistically significant (p<0.05) relative to the cells harboring the WT genomes, although the difference in the frequency of any one abnormality did not reach statistical significance (Figure 3C and 3D ).

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