Prognostic value of loss of heterozygosity and sub-cellular localization of SMAD4 varies with tumor stage in colorectal cancer.

Oncotarget · 2017 · PMC5386755 · PMID 28423626

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

marginally statistically significantP = 0.07so close (0.05 < p ≤ 0.1)

For the overall sample, there was a marginally statistically significant association between low nuclear SMAD4 IHC levels and poorer survival of these patients (log-rank, P = 0.07) (data not shown).

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failed to reach statistical significanceno p-value reported

Although there was an association for stage I patients, this relationship failed to reach statistical significance due to only seven events (deaths due to CRC) among these patients.

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borderline significantno p-value reported

Further, a borderline significant shorter survival was found for those with low SMAD4 protein levels in the nuclei with Smad4 LOH positive in stage III CRC patients, indicating that Smad4 is a tumor suppressor gene for these 18q21 deletions at the Smad4 locus.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.