Biophysical properties, thermal stability and functional impact of 8-oxo-7,8-dihydroguanine on oligonucleotides of RNA-a study of duplex, hairpins and the aptamer for preQ1 as models.

Nucleic Acids Res · 2017 · PMC5389535 · PMID 28426093

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showed a trendno p-value reported

UV-vis spectra showed a trend displaying higher hypochromicity in the band at ca. 290 nm as a function of increasing number of modifications, thus confirming the presence of the lesion (s) (Figure 1B and Supplementary Data , Supplementary Figure S49 for UV-vis spectra comparison of of 8-oxo-7,8-dihydroguanosine and guanosine).

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