In particular, there was a slight trend toward increased 28-day mortality in both subgroups after MARS treatment compared to SMT: 28-day mortality in patients with acute liver injury (MARS 5.3% (95% CI: 0–15.3%); SMT 3.3% (95% CI: 0–9.8), p = 0.754) and in those with GD (MARS 20.0% (95% CI: 0–44.7), SMT 11.1% (95% CI: 0–31.7), p = 0.478).
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Molecular adsorbent recirculating system (MARS) in acute liver injury and graft dysfunction: Results from a case-control study.
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Similar to the classification of the patients with acute liver injury, the classification of the patients with GD according to the response criteria showed a trend toward a better short-term response in the MARS group than in the SMT group ( Fig 3B ).