Randomized Trial of Adding Parenteral Acetaminophen to Prochlorperazine and Diphenhydramine to Treat Headache in the Emergency Department.

West J Emerg Med · 2017 · PMC5391886 · PMID 28435487

Europe PMC DOI

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did not reach statistical significanceno p-value reported

Forty-one patients required some form of “rescue” medication in addition to the initially administered medications; 17/45 (38%) of patients who received IV acetaminophen required rescue analgesia, as opposed to 24/45 (53%) of patients in the placebo group, which did not reach statistical significance.

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