Benefit of tolvaptan in the management of hyponatraemia in patients with diuretic-refractory congestive heart failure: the SEMI-SEC project.

ESC Heart Fail · 2017 · PMC5396041 · PMID 28451449

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did not reach statistical significanceno p-value reported

Glomerular filtration at the end of treatment was related with an improvement in sodium levels and urine output, although overall increases in glomerular filtration did not reach statistical significance.

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