MCL-1 is modulated in Crohn's disease fibrosis by miR-29b via IL-6 and IL-8.

Cell Tissue Res · 2017 · PMC5397660 · PMID 28190086

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

approached significancep = 0.06so close (0.05 < p ≤ 0.1)

IL8 mRNA levels were also up-regulated by pre-miR-29b and approached significance ( p = 0.06; Fig. 5b ).

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did not quite reach significanceno p-value reported

These results demonstrate that miR-29b up-regulates the expression of IL6 and IL8 at the mRNA level, although this change did not quite reach significance for IL8 (Fig. 5 ) and their release into the supernatant.

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