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The valosin-containing protein is a novel mediator of mitochondrial respiration and cell survival in the heart in vivo.

Sci Rep · 2017 · PMC5397870 · PMID 28425440

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4b , although there was a modest increase in state 2 respiration rate in the mitochondria from VCPTG mice vs WT, the difference did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.