The Trend-in-trend Research Design for Causal Inference.

Epidemiology · 2017 · PMC5398952 · PMID 27775954

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

a strong trendno p-value reported

The main limitations of the trend-in-trend method are the need for a strong trend in exposure prevalence and the reduced statistical precision that accompanies group-level rather than individual-level analyses.

also in 5,725 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.