Slight apoptosis protection by LPS in primary neutrophils was visible by 20 h but this did not reach statistical significance, whereas GM-CSF treatment substantially protected against cell death ( Supplementary Figure S3B ).
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The anti-apoptotic Bcl-2 family protein A1/Bfl-1 regulates neutrophil survival and homeostasis and is controlled via PI3K and JAK/STAT signaling.
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