Joint Assessment of Donor and Recipient hTERT Gene Polymorphism Provides Additional Information for Early Kidney Transplantation Outcomes.

Med Sci Monit · 2017 · PMC5400029 · PMID 28410362

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0900

boldest claim

The sentences

on the borderline of significancep =0.06so close (0.05 < p ≤ 0.1)

On the other hand, though distribution of analyzed genotype pairs revealed no significant differences with regard to DGF, the multiple logistic regression analysis adjusted for donor’s and recipient’s age and gender showed that rs2735940 hTERT TT donor’s genotype was an independent factor decreasing the risk for DGF on the borderline of significance (OR=0.41; 95% CI: 0.16–1.07; p =0.06) and that rs2735940 hTERT TT recipient’s genotype was an independent factor significantly increasing the risk for DGF (OR=2.47; 95% CI: 1.06–5.79; p =0.03) ( Table 3 ).

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a borderline significant trendp =0.09so close (0.05 < p ≤ 0.1)

However, in recipients with AR compared to those without AR, the distribution of rs2735940 hTERT polymorphism genotype pairs differed significantly ( p =0.04) and in the case of rs7235755 chromosome 18 polymorphisms genotype pairs distribution, a borderline significant trend was observed ( p =0.09).

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