Ipilimumab treatment decreases monocytic MDSCs and increases CD8 effector memory T cells in long-term survivors with advanced melanoma.

In contrast to the dynamics of CD4 + PD1 + T cells, a strong trend towards a decrease in the CD8 + PD1 + T cell population was observed (Figure 3E ).

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In this case, ipilimumab treatment resulted in a highly significant decrease in the frequency of this population at the nine-week time point.

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