Asthma-COPD overlap syndrome (ACOS) in primary care of four Latin America countries: the PUMA study.

Finally, when considering and interpreting the current findings, it is important to be aware of the following study limitations: these results are not generalizable to all Latin American countries as the study was only performed in four countries; it is possible that some results did not reach statistical significance as a result of sample size and lack of power, despite the efforts made to ensure a representative sample.

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