Heartworm extract induces relaxation of isolated rat thoracic aorta.

In contrast, relaxation due to HC extract treatment decreased from 37.2 ± 9.2% to 17.0 ± 17.2% after treatment with 300 μ M L-NAME, but the difference did not reach statistical significance ( P =0.1185) ( Fig. 4A left , middle and 4B ).

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