In the rostral-caudal direction, the significant main effect of the region was identified for both MPF (F = 144.37, p < 0.001) and LFB (F = 7.64, p < 0.02), while interactions between the effects of treatment and region did not reach statistical significance (F = 1.74, p = 0.21 for MPF and F = 2.84, p = 0.13 for LFB).
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Histological validation of fast macromolecular proton fraction mapping as a quantitative myelin imaging method in the cuprizone demyelination model.
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