Secondary End Points At month 3, the mean ADAS-cog+ score had improved in both groups (−5.4 [0.53] for Actovegin and −4.3 [0.52] for placebo), but the LS mean treatment difference did not reach statistical significance (−1.1; 95% CI, −2.6, 0.3; P =0.12).
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ARTEMIDA Trial (A Randomized Trial of Efficacy, 12 Months International Double-Blind Actovegin): A Randomized Controlled Trial to Assess the Efficacy of Actovegin in Poststroke Cognitive Impairment.
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