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Opium use during pregnancy and risk of preterm delivery: A population-based cohort study.

PLoS One · 2017 · PMC5407680 · PMID 28448546

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When we also adjusted for hypertension during pregnancy and small for gestational age, the association between opium use and caesarean section preterm delivery was attenuated: the point estimates moved toward the null and did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.