However, by six months of age, scotopic a-wave responses at higher intensities showed a trend towards lower amplitudes ( Fig 6C ) and b-wave amplitudes were significantly reduced in SIRT6 KO animals as compared with WT and HET mice ( Fig 6D ).
1
—
—
However, by six months of age, scotopic a-wave responses at higher intensities showed a trend towards lower amplitudes ( Fig 6C ) and b-wave amplitudes were significantly reduced in SIRT6 KO animals as compared with WT and HET mice ( Fig 6D ).