In particular, preadministration of 3 mg/kg JWH-133 produced a decrease in cocaine-induced stimulation of horizontal activity that did not reach statistical significance, while the respective decrease following the 10 mg/kg dose was statistically significant.
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Attenuation of Cocaine-Induced Conditioned Place Preference and Motor Activity via Cannabinoid CB2 Receptor Agonism and CB1 Receptor Antagonism in Rats.
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