Role of Pattern Recognition Receptors in the Modulation of Antimicrobial Peptide Expression in the Corneal Epithelial Innate Response to F. solani.

hBD1 expression also was enhanced by Zymosan challenge alone at 6 and 12 hours but this did not reach statistical significance. hBD2 expression ( Fig. 2 B) was significantly increased 6 hours after treatment with Zymosan, Zymosan Depleted, and the combination of the two: 50.0 ± 9.9, 37.1 ± 9.8, 450.1 ± 94.1 ( P < 0.05, 0.05, and 0.001 respectively).

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