Expression of Herpes Simplex Virus Thymidine Kinase/Ganciclovir by RNA Trans-Splicing Induces Selective Killing of HIV-Producing Cells.

Mol Ther Nucleic Acids · 2017 · PMC5415956 · PMID 28624190

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closest p

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did not reach statistical significanceno p-value reported

BD-A7 and BD-A5 were effective in reducing cell viability in the presence of pNL4.3, and BD-A3 had a modest effect, although for these constructs this did not reach statistical significance in all three independent experiments.

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may be significantno p-value reported

The association of the longest binding domain with the greatest effect on GCV-mediated, HIV-dependent cell killing may be significant.

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