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Experimental approach to IGF-1 therapy in CCl<sub>4</sub>-induced acute liver damage in healthy controls and mice with partial IGF-1 deficiency.

J Transl Med · 2017 · PMC5418730 · PMID 28472963

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Regarding the gene expression of MMPs ( Mmp2 , Mmp13 , Mmp9 , and Adam11 ), an expected increase after CCl 4 injury was observed and accompanied by a reduction after IGF-1 therapy that did not reach statistical significance.

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