Exogenous alpha 1-antitrypsin down-regulates SERPINA1 expression.

PLoS One · 2017 · PMC5423693 · PMID 28486562

Europe PMC DOI

hedged sentence

0.0539

closest p · 1.1× alpha

0.0539

boldest claim

The sentences

did not reach statistical significanceP = 0.0539so close (0.05 < p ≤ 0.1)

Although it did not reach statistical significance (P = 0.0539)—analysis of lung tissues showed lower SERPINA1 expression in PiZZ emphysema patients receiving augmentation therapy relative to those without therapy.

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