Pharmacokinetic and Pharmacodynamic Properties of Faster-Acting Insulin Aspart versus Insulin Aspart Across a Clinically Relevant Dose Range in Subjects with Type 1 Diabetes Mellitus.

In another phase III study in subjects with T2DM treated in a basal-bolus regimen plus metformin, the reduction from baseline in 1-h postprandial glucose increments was statistically significantly greater for faster aspart versus insulin aspart in a meal-test, while the difference in the reduction from baseline in 2-h postprandial glucose increments in favour of faster aspart did not reach statistical significance [ 21 ].

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