Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia.

Sci Rep · 2017 · PMC5429805 · PMID 28404991

Europe PMC DOI

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0.1300

closest p · 2.6× alpha

0.1300

boldest claim

The sentences

did not reach statistical significancep = 0.13not close (p > 0.1)

We found a reduction in the number of Paneth cells, specialized crypt cells involved in immunity and production of antimicrobial compounds, in all three sections of the small intestine of PPAR δ IEC-KO mice, although this did not reach statistical significance (median 1.5 [0.5–3.0] vs 2.0 [1.0–3.0], p = 0.13).

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