Pre-treatment with rhGDF15 significantly reduced (p ≤ 0.05) the levels of Annexin V + cells, but not double positive cells, although a decreasing trend was seen.
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Growth Differentiation Factor-15 Deficiency Augments Inflammatory Response and Exacerbates Septic Heart and Renal Injury Induced by Lipopolysaccharide.
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There was also a smaller reduction in FS% in TG mice, but it did not reach statistical significance (Fig. 1D ).