Comparison of artemether-lumefantrine and chloroquine with and without primaquine for the treatment of Plasmodium vivax infection in Ethiopia: A randomized controlled trial.

PLoS Med · 2017 · PMC5433686 · PMID 28510573

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.0590

boldest claim

The sentences

did not reach statistical significancep = 0.059so close (0.05 < p ≤ 0.1)

However, despite CQ’s compromised efficacy, the risk of recurrence was almost 2-fold greater in patients treated with AL alone compared to those treated with CQ alone, although this difference did not reach statistical significance ( p = 0.059).

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of borderline significancep = 0.059so close (0.05 < p ≤ 0.1)

In those not prescribed PQ, the risk of recurrence by day 42 was greater following AL than CQ, although this difference was of borderline significance (HR = 1.8 [95% CI 1.0–3.2], p = 0.059) ( Table 3 ).

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