showed a trendp=0.07
Men were significantly more likely to have a thin/ruptured fibrous cap (48% vs 17%, p<0.01) and lipid-rich/necrotic core (73% vs 50%, p<0.01) and showed a trend towards more haemorrhage (33% vs 17%, p=0.07). 28 Another study of 763 patients in which histological analysis was performed on carotid plaques found that plaques from men had higher rates of cellularity, more inflammatory infiltrates and less calcification. 29 Increased incidence of high-risk plaque features in men may contribute to explanation of greater benefit of CEA in men versus women.