entomophila , qRT-PCR analysis showed a 2-fold decrease in acsA expression of the Δ crbS sensor kinase mutant compared to that of the wild-type strain transformed with an empty vector (pPSV38) ( Fig 2A ), although this difference did not reach statistical significance.
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Regulation of acetyl-CoA synthetase transcription by the CrbS/R two-component system is conserved in genetically diverse environmental pathogens.
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