Neuroserpin polymers cause oxidative stress in a neuronal model of the dementia FENIB.

In this analysis, we included three additional genes involved in oxidative stress, namely Gpx 1 (coding for glutathione peroxidase 1), Sod 2 (coding for superoxide dismutase 2) and Cat (coding for catalase), which showed a trend towards up-regulation in G392E NS cells in our RNA sequencing dataset, although not statistically significant due to high variability in the three replicates used for RNA sequencing analysis ( Supplementary Table 1 , Fig. 4 C, Fig.

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