Long-term effect of neonatal inhibition of APP gamma-secretase on hippocampal development in the Ts65Dn mouse model of Down syndrome.

Neurobiol Dis · 2017 · PMC5439029 · PMID 28359846

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only marginally significantno p-value reported

Treatment caused a reduction in p21 levels in Ts65Dn mice although this effect was only marginally significant ( Fig. 5 C).

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