Deterioration of quality of life is associated with the exacerbation frequency in individuals with alpha-1-antitrypsin deficiency - analysis from the German Registry.

Int J Chron Obstruct Pulmon Dis · 2017 · PMC5439990 · PMID 28553095

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showed a trendno p-value reported

In inter-group comparison of all quartiles (I–IV), patients with higher deterioration in SGRQ score reported more often an increase of medication ( P =0.035) and more frequent hospitalizations ( P =0.036), while the need for corticosteroids ( P =0.077) and antibiotics ( P =0.394) only showed a trend.

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