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Comparison of Sirtuin 3 Levels in ALS and Huntington's Disease-Differential Effects in Human Tissue Samples vs. Transgenic Mouse Models.

Front Mol Neurosci · 2017 · PMC5445120 · PMID 28603486

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a decreasing trendno p-value reported
In the cortex of PGC-1α KO mice Sirt3 (Supplementary Figures 4A,C, 10) mRNA and SIRT3 protein levels also showed a decreasing trend, without reaching statistical significance (Figures 5B,D , Supplementary Figure 11), whereas Sirt4 and Sirt5 mRNA levels were evenly distributed (Supplementary Figures S4B,D).

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showed a trendno p-value reported
Our experiments showed a trend towards reduced Sirt3 mRNA levels in PGC-1α KO mice compared to wt littermate controls.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.