Functional Properties of Human NMDA Receptors Associated with Epilepsy-Related Mutations of GluN2A Subunit.

Front Cell Neurosci · 2017 · PMC5447064 · PMID 28611597

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did not reach statistical significanceno p-value reported

In contrast with the two other variants studied here, p.Ala716Thr-GluN2A had weaker effect on NMDAR functioning, at least according to the parameters that were analyzed: hence surface expression and desensitization parameters were similar to control values, and the changes in current amplitude did not reach statistical significance.

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