The Effect of Antibiotic Exposure and Specimen Volume on the Detection of Bacterial Pathogens in Children With Pneumonia.

Trends were consistent when limited to the subgroup of CXR-positive, HIV-uninfected cases, but did not reach statistical significance (Supplementary Table 2).

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These findings are similar to those in a study of an elderly population in Finland where detection of pneumococcus was significantly reduced for NP culture and showed a nonsignificant trend toward reduction by PCR [ 22 ].

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