Identification of a three-gene expression signature of poor-prognosis breast carcinoma.

Mol Cancer · 2004 · PMC544833 · PMID 15606925

Europe PMC DOI

hedged sentences

0.2000

closest p · 4.0× alpha

0.2700

boldest claim

The sentences

near-significantP < 0.2not close (p > 0.1)

Using a Cox proportional hazards model, we also assessed the prognostic value, for RFS, of parameters that were significant or near-significant (P < 0.2) in univariate analysis, i.e.

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a trend towards significanceP = 0.27not close (p > 0.1)

SBR grade, lymph-node status, macroscopic tumor size (Table 2 ) and the three-gene expression signature (Figure 1B ), only SBR grade was an independent predictor of RFS (P = 0.00023); the three-gene expression signature only showed a trend towards significance (P = 0.27).

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