We found that the frequency of BM CD14 + MDSCs inversely correlated with the frequency of Ki67 + CD8 + T cells in BM, PBMC, spleen, ALN, but not MLN, liver, ileum LP and colonic LP (although MLN and colonic LP showed nearly significant trends) ( Fig 9A–9H ); whereas Lin - CD15 + MDSC did not correlate with the frequency of Ki67 + CD8 + T cells in any of the compartments except PBMC ( S9 Fig ).
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Paradoxical myeloid-derived suppressor cell reduction in the bone marrow of SIV chronically infected macaques.
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