Barely Significant
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Oxidative stress induces stem cell proliferation via TRPA1/RyR-mediated Ca<sup>2+</sup> signaling in the <i>Drosophila</i> midgut.

Elife · 2017 · PMC5451214 · PMID 28561738

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quite significantno p-value reported
However, there are two remaining issues that are quite significant, and really need to be addressed before acceptance, as outlined below: 1) One reviewer and the reviewing editor still believe the manuscript still falls short of establishing how, mechanistically, [Ca 2+ ] activates ERK.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.