Inflammation Downregulates UCP1 Expression in Brown Adipocytes Potentially via SIRT1 and DBC1 Interaction.

The decrease in Ucp1 ( Figure 4 A) and Dio2 ( Figure 4 D) expression did not reach statistical significance, whereas the inhibition of Prdm16 and Cidea after LPS treatment was significant ( Figure 4 B,C).

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