Enhanced expression and phosphorylation of Sirt7 activates smad2 and ERK signaling and promotes the cardiac fibrosis differentiation upon angiotensin-II stimulation.

PLoS One · 2017 · PMC5459426 · PMID 28582407

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a significant trendno p-value reported

In particular for vinculin, our results also demonstrate a significant trend of reduced protein expression in Sirt7 siRNA plus Ang-II-treated cells compared with Ang-II alone, even at the same level as the negative control group.

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