Single-cell entropy for accurate estimation of differentiation potency from a cell's transcriptome.

Although of marginal significance, signalling entropy was higher in the CTCs from patients exhibiting resistance (Wilcox test P =0.047, Fig. 5e ).

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Moreover, at embryonic day 18, it could discriminate alveolar type cells from a recently discovered bipotent progenitor subgroup 29 , albeit with marginal significance due to small cell numbers ( Supplementary Fig. 3A ).

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